Table 2 Chemical by-products found in reference aerosol
From: Universal electronic-cigarette test: physiochemical characterization of reference e-liquid
| Name | GHS signal word | Hazard classification | CAS number | S/N ratio based on TIC peak intensity |
|---|---|---|---|---|
| Nicotine | Danger |
Acute Toxicity 2 Acute Aquatic Toxicity 1 Chronic Aquatic Toxicity 1 Fatal if swallowed or in contact with skin | 54–11–5 | 115578.89 |
| Nicotyrine | Danger |
Skin Irritation 3 Acute Toxicity 3 Respiratory Irritation 3 | 487–19–4 | 1405.67 |
| Propylene glycol | None | None | 57–55–6 | 709.6 |
| 4–Pyridinecarboxaldehyde | Warning |
Skin Irritation 2 Eye Irritation 2A STOT SE 3 Combustible liquid Harmful if swallowed May cause respiratory irritation | 872–85–5 | 74.1 |
| 2,4,7-trimethyl-1,8-naphthyridine | NF | NF | 14757–44–9 | 59.46 |
| 1-Butanol | Danger |
Flammable liquid 3 Acute Toxicity 4 Skin Irritation 2 Eye Damage 1 STOT SE 3 Harmful if swallowed May cause respiratory irritation May cause drowsiness | 71–36–3 | 31.09 |
| Cotinine | Warning |
Acute Toxicity 4 Skin Irritation 2 Eye Irritation 2A STOT SE 3 Harmful if swallowed May cause respiratory irritation | 486–56–6 | 27.66 |
| 5-Methyl-2-heptanol | Danger |
Acute Toxicity. 3 Harmful if swallowed | 54630–50–1 | 25.07 |
| 1-Methoxy butane | Danger | Flammable liquid | 628–28–4 | 24.8 |
| 3-(3,4-dihydro-2H-pyrrol-5-yl) pyridine | Warning |
Acute Toxicity 4 Skin Irritation 2 Eye Irritation 2A STOT SE 3 Harmful if swallowed May cause respiratory irritation | 532–12–7 | 22.44 |
| 1-(4-pyridinylmethyl)-1H-pyrazol-5-amine | Danger |
Acute Toxicity. 3 Harmful if swallowed | 3524–31–0 | 18.12 |
| 2,3-dihydro-1H-inden-1-one | None | None | 83-33-0 | 17.01 |
| 2-methyl 2-pentanol | Warning |
Flammable liquid 3 Skin Irritation 2 Eye Irritation 2A STOT SE 3 May cause respiratory irritation | 590–36–3 | 14.99 |
| 3-Ethyl-5-hexen-3-ol | Danger |
Skin Irritation 2 Eye Damage 1 STOT SE 3 Acute Aquatic Toxicity 3 Chronic Aquatic Toxicity 3 May cause respiratory irritation | 1907–46–6 | 8.79 |
| 6-Methyl-1,2,3,4-tetrahydroquinoline | Warning |
Acute Toxicity 4 Skin Irritation. 2 Eye Irritation 2A STOT SE 3 Harmful if swallowed May cause respiratory irritation | 91–61–2 | 8.79 |
| 1-(p-Toluidio)-1-deoxy-beta-d-idopyranose | NF | NF | 2870–82–8 | 8.75 |